Two sample MR report
CD55_Monocyte (Mono) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.1239430 | 0.1721906 | 0.5236571 |
| Weighted median | 5 | -0.0936328 | 0.0252908 | 0.0002137 |
| Inverse variance weighted | 5 | -0.0827458 | 0.0190825 | 0.0000145 |
| Simple mode | 5 | -0.0935735 | 0.0323033 | 0.0442635 |
| Weighted mode | 5 | -0.0940263 | 0.0299354 | 0.0348152 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.878928 | 3 | 0.2748380 |
| Inverse variance weighted | 3.954135 | 4 | 0.4122486 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0170294 | 0.0706099 | 0.8249627 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002262 | 0 | TRUE | 0.1565279 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
